Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tnc  tenascin C   (Synonyms: C130033P17Rik, cytotactin, hexabrachion, Hxb, tenascin-C, TN, TN-C)
Results	Reference
1*	J:279777 Arno B, Galli F, Roostalu U, Aldeiri BM, Miyake T, Albertini A, Bragg L, Prehar S, McDermott JC, Cartwright EJ, Cossu G, TNAP limits TGF-beta-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors. J Cell Sci. 2019 Aug 8;132(15):jcs234948
1*	J:152889 Aufderheide E, Chiquet-Ehrismann R, Ekblom P, Epithelial-mesenchymal interactions in the developing kidney lead to expression of tenascin in the mesenchyme. J Cell Biol. 1987 Jul;105(1):599-608
1*	J:153111 Aufderheide E, Ekblom P, Tenascin during gut development: appearance in the mesenchyme, shift in molecular forms, and dependence on epithelial-mesenchymal interactions. J Cell Biol. 1988 Dec;107(6 Pt 1):2341-9
1	J:80740 Bartsch U, Bartsch S, Dorries U, Schachner M, Immunohistological Localization of Tenascin in the Developing and Lesioned Adult Mouse Optic Nerve. Eur J Neurosci. 1992;4(4):338-352
1	J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83
1	J:332651 Brent AE, Buchholtz EA, Mansfield JH, Evolutionary assembly and disassembly of the mammalian sternum. Curr Biol. 2023 Jan 9;33(1):197-205.e2
1	J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9)
1	J:112203 Chinoy MR, Miller SA, Relevance of tenascin-C and matrix metalloproteinases in vascular abnormalities in murine hypoplastic lungs. Biol Neonate. 2006;90(3):185-96
1*	J:152827 Crossin KL, Hoffman S, Tan SS, Edelman GM, Cytotactin and its proteoglycan ligand mark structural and functional boundaries in somatosensory cortex of the early postnatal mouse. Dev Biol. 1989 Dec;136(2):381-92
1	J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400
1	J:166772 DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE, Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol. 2010;10:112
1	J:202029 Folgueras AR, Guo X, Pasolli HA, Stokes N, Polak L, Zheng D, Fuchs E, Architectural niche organization by LHX2 is linked to hair follicle stem cell function. Cell Stem Cell. 2013 Sep 5;13(3):314-27
1	J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89
1	J:85490 Fukushi J, Inatani M, Yamaguchi Y, Stallcup WB, Expression of NG2 proteoglycan during endochondral and intramembranous ossification. Dev Dyn. 2003 Sep;228(1):143-8
1	J:30009 Gates MA, Thomas LB, Howard EM, Laywell ED, Sajin B, Faissner A, Gotz B, Silver J, Steindler DA, Cell and molecular analysis of the developing and adult mouse subventricular zone of the cerebral hemispheres. J Comp Neurol. 1995 Oct 16;361(2):249-66
1	J:266597 Hartman BH, Bscke R, Ellwanger DC, Keymeulen S, Scheibinger M, Heller S, Fbxo2(VHC) mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination. Dev Biol. 2018 Nov 1;443(1):64-77
1	J:330532 Hennen E, Czopka T, Faissner A, Structurally distinct LewisX glycans distinguish subpopulations of neural stem/progenitor cells. J Biol Chem. 2011 May;286(18):16321-31
1	J:212598 Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E, NFATc1 balances quiescence and proliferation of skin stem cells. Cell. 2008 Jan 25;132(2):299-310
1	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
1	J:150213 Huang Z, Wang D, Ihida-Stansbury K, Jones PL, Martin JF, Defective pulmonary vascular remodeling in Smad8 mutant mice. Hum Mol Genet. 2009 Aug 1;18(15):2791-801
1	J:345111 Jacobson KR, Saleh AM, Lipp SN, Tian C, Watson AR, Luetkemeyer CM, Ocken AR, Spencer SL, Kinzer-Ursem TL, Calve S, Extracellular matrix protein composition dynamically changes during murine forelimb development. iScience. 2024 Feb 16;27(2):108838
1	J:306540 Jiang D, Correa-Gallegos D, Christ S, Stefanska A, Liu J, Ramesh P, Rajendran V, De Santis MM, Wagner DE, Rinkevich Y, Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring. Nat Cell Biol. 2018 Apr;20(4):422-431
1	J:17225 Julian J, Chiquet-Ehrismann R, Erickson HP, Carson DD, Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion. Development. 1994 Mar;120(3):661-71
1	J:42541 Kalembey I, Yoshida T, Iriyama K, Sakakura T, Analysis of tenascin mRNA expression in the murine mammary gland from embryogenesis to carcinogenesis: an in situ hybridization study. Int J Dev Biol. 1997 Aug;41(4):569-73
1	J:135623 Klausmeyer A, Garwood J, Faissner A, Differential expression of phosphacan/RPTPbeta isoforms in the developing mouse visual system. J Comp Neurol. 2007 Oct 20;504(6):659-79
1	J:155292 Levay AK, Peacock JD, Lu Y, Koch M, Hinton RB Jr, Kadler KE, Lincoln J, Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo. Circ Res. 2008 Oct 24;103(9):948-56
1	J:260363 Liang Q, Xia W, Li W, Jiao J, RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain. Cell Death Differ. 2018 Feb;25(2):294-306
1*	J:90275 Lincoln J, Alfieri CM, Yutzey KE, Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos. Dev Dyn. 2004 Jun;230(2):239-50
1	J:335095 Lipp SN, Jacobson KR, Schwaderer AL, Hains DS, Calve S, FOXD1 is required for 3D patterning of the kidney interstitial matrix. Dev Dyn. 2023 Apr;252(4):463-482
1	J:182166 Liu CF, Aschbacher-Smith L, Barthelery NJ, Dyment N, Butler D, Wylie C, Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon. Tissue Eng Part A. 2012 Mar;18(5-6):598-608
1	J:263505 Liu G, Cooley MA, Jarnicki AG, Hsu AC, Nair PM, Haw TJ, Fricker M, Gellatly SL, Kim RY, Inman MD, Tjin G, Wark PA, Walker MM, Horvat JC, Oliver BG, Argraves WS, Knight DA, Burgess JK, Hansbro PM, Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases. JCI Insight. 2016 Jun 16;1(9):e86380
1	J:22448 Matsumoto K, Saga Y, Ikemura T, Sakakura T, Chiquet-Ehrismann R, The distribution of tenascin-X is distinct and often reciprocal to that of tenascin-C. J Cell Biol. 1994 Apr;125(2):483-93
1	J:309403 Nakagawa N, Xin C, Roach AM, Naiman N, Shankland SJ, Ligresti G, Ren S, Szak S, Gomez IG, Duffield JS, Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis. Kidney Int. 2015 Jun;87(6):1125-40
1*	J:13269 Ocklind G, Talts J, Fassler R, Mattsson A, Ekblom P, Expression of tenascin in developing and adult mouse lymphoid organs. J Histochem Cytochem. 1993 Aug;41(8):1163-9
1	J:313370 Pena-Jimenez D, Fontenete S, Megias D, Fustero-Torre C, Grana-Castro O, Castellana D, Loewe R, Perez-Moreno M, Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo. EMBO J. 2019 Oct 1;38(19):e101688
1	J:156199 Robel S, Mori T, Zoubaa S, Schlegel J, Sirko S, Faissner A, Goebbels S, Dimou L, Gotz M, Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis. Glia. 2009 Nov 15;57(15):1630-47
1*	J:36890 Saga Y, Yagi T, Ikawa Y, Sakakura T, Aizawa S, Mice develop normally without tenascin. Genes Dev. 1992 Oct;6(10):1821-31
1	J:87910 Scherberich A, Tucker RP, Samandari E, Brown-Luedi M, Martin D, Chiquet-Ehrismann R, Murine tenascin-W: a novel mammalian tenascin expressed in kidney and at sites of bone and smooth muscle development. J Cell Sci. 2004 Feb 1;117(Pt 4):571-81
1*	J:137171 Shay EL, Greer CA, Treloar HB, Dynamic expression patterns of ECM molecules in the developing mouse olfactory pathway. Dev Dyn. 2008 Jul;237(7):1837-50
1	J:39158 Talts JF, Eng H, Zhang HY, Faissner A, Ekblom P, Characterization of monoclonal antibodies against tenascin-C: no apparent effect on kidney development in vitro. Int J Dev Biol. 1997 Feb;41(1):39-48
1*	J:153112 Thesleff I, Mackie E, Vainio S, Chiquet-Ehrismann R, Changes in the distribution of tenascin during tooth development. Development. 1987 Oct;101(2):289-96
1	J:151326 Treloar HB, Ray A, Dinglasan LA, Schachner M, Greer CA, Tenascin-C is an inhibitory boundary molecule in the developing olfactory bulb. J Neurosci. 2009 Jul 29;29(30):9405-16
1*	J:310857 Welcker D, Stein C, Feitosa NM, Armistead J, Zhang JL, Lutke S, Kleinridders A, Bruning JC, Eming SA, Sengle G, Niehoff A, Bloch W, Hammerschmidt M, Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep. 2021 Sep 9;11(1):17926
1	J:139011 Wilkinson GA, Schittny JC, Reinhardt DP, Klein R, Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity. Dev Dyn. 2008 Aug;237(8):2220-34
1	J:195242 Youssef KK, Lapouge G, Bouvree K, Rorive S, Brohee S, Appelstein O, Larsimont JC, Sukumaran V, Van de Sande B, Pucci D, Dekoninck S, Berthe JV, Aerts S, Salmon I, del Marmol V, Blanpain C, Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation. Nat Cell Biol. 2012 Dec;14(12):1282-94
1	J:36639 Yuasa S, Bergmann glial development in the mouse cerebellum as revealed by tenascin expression. Anat Embryol (Berl). 1996 Sep;194(3):223-34
1	J:70858 Zhou XH, Brakebusch C, Matthies H, Oohashi T, Hirsch E, Moser M, Krug M, Seidenbecher CI, Boeckers TM, Rauch U, Buettner R, Gundelfinger ED, Fassler R, Neurocan is dispensable for brain development. Mol Cell Biol. 2001 Sep;21(17):5970-8